Ovarian Hyperstimulation Syndrome

This is a rare complication resulting from IVF/ICSI and is more often seen in patients with very sensitive ovaries, such as those who suffer from PCOS (Polycystic Ovarian Syndrome)

Symptoms may appear after the final hCG (Pregnyl) injection that include the following:-
  • Abdominal distention (swelling)
  • Diarrhea
  • Shortness of breath
  • Nausea/Vomiting
  • Dehydration and poor urine output
In cases of ovarian hyperstimulation the small blood vessels in the multiple follicles, which are on the ovaries, leak fluid, which is high in protein into the abdominal cavity. It is this leaking of fluid which gives rise to the abdominal bloating and distention and the other symptoms, namely nausea, vomiting, diarrhea, etc.  The vast majority of cases of ovarian hyperstimulation are mild and the symptoms will resolve spontaneously. The only supportive treatment usually required is drinking plenty of fluids. Occasionally however a more severe form of hyperstimulation syndrome can occur and for this hospital admission may be required.

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The Centre for Reproductive and Genetic Health (CRGH)
The New Wing - Eastman Dental Hospital
256 Gray's Inn Road - London WC1X 8LD
t: 020 7837 2905 w: www.crgh.co.uk
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